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Usp9x: Promising therapeutic target for pancreatic cancer

Curator: Ritu Saxena, Ph.D. Introduction and Research Relevance: Pancreatic ductal adenocarcinoma (PDA) is the fourth leading cause of cancer death in the United States with a median survival of <6...

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How mobile elements in “Junk” DNA promote cancer. Part 1: Transposon-mediated...

Stephen J. Williams, Ph.D.; Author-Writer-Curator.  Landscape of Somatic Retrotransposition in Human Cancers. Science (2012); Vol. 337:967-971. (1) Sequencing of the human genome via massive programs...

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Sensors and Signaling in Oxidative Stress

Sensors and Signaling in Oxidative Stress Author: Larry H. Bernstein, MD, FCAP   This important article on oxidative stress was published in Free Radical Biol. and Med. Nrf2:INrf2(Keap1) Signaling in...

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Loss of Gene Islands May Promote a Cancer Genome’s Evolution: A new...

Loss of Gene Islands May Promote a Cancer Cell’s Survival, Proliferation and Evolution: A new Hypothesis (and second paper validating model) on Oncogenesis from the Elledge Laboratory Writer, Curator:...

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DNA mutagenesis and DNA repair

DNA mutagenesis and DNA repair Larry H. Bernstein, MD, FCAP, Curator Leaders in Pharmaceutical Intelligence – Series E (2; 2.11) Evelyn M. Witkin, born Evelyn Maisel is an American geneticist who was...

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Rhodopsin role in ciliary trafficking

Rhodopsin role in ciliary trafficking Jillian N Pearring Department of Ophthalmology, Duke University School of Medicine, Durham, United States No competing interests declared ”...

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Acute Changes in Serotonin Detected by AI-designed Serotonin Sensor

Reporter: Adina Hazan, PhD Elizabeth Unger from the Tian group at UC Davis, Jacob Keller from the Looger lab from HHMI, Michael Altermatt from the Gradinaru group at California Institute of Technology,...

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